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MBF Bioscience stereoinvestigator software
Stereoinvestigator Software, supplied by MBF Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/stereoinvestigator+software/stereoinvestigator+software/bio_rxiv__2025__07__13__664600-249-17-19
Average 90 stars, based on 1 article reviews
stereoinvestigator software - by Bioz Stars, 2026-11
90/100 stars

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Software:

Article Title: Stool-derived extracellular vesicles increase inflammasome signaling and regulate the gut-brain axis after stroke in Alzheimer's disease transgenic mice.
Article Snippet: Patients with Alzheimer’s disease (AD) suffering from post-stroke gut dysfunction present with worsened neurological outcomes.. This study investigated the role of stool-derived extracellular vesicle (EV)-mediated inflammasome signaling in the gut-brain axis following photothrombotic stroke (PTS) in aged 3xTgAD and wildtype (WT) mice.. Western Blot and immunohistochemical analyses evaluated inflammasome signaling proteins, Gasdermin D (GSDMD), and Aβ in intestinal and cortical tissues.

Article Title: Development of human targeted extracellular vesicles loaded with shRNA minicircles to prevent parkinsonian pathology
Article Snippet: .. The total number of dopaminergic neurons within the SNc was assessed by stereology in every fourth section spanning the entire SNc using StereoInvestigator software (MBF Bioscience, Williston, VT) as previously described [ ]. ..

Article Title: Targeting Neuromuscular Junction Regeneration is a Therapeutic Strategy in ALS
Article Snippet: .. The Optical Fractionator stereological technique was employed using a computer-assisted Nikon Eclipse E600 microscope equipped with the StereoInvestigator software (MicroBrightField Inc., Williston, VT, USA) ( West et al , 1991 ). .. 50 μm thick, free-floating coronal sections of each spinal cord level were cut using a cryostat (Leica), then stored in an anti-freeze solution (30% ethylene glycol, 30% glycerol, 10% PB; 189 mM NaH 2 PO 4 ; 192.5 mM NaOH; pH 7.4) at −20°C until being used.

Article Title: Development of human targeted extracellular vesicles loaded with shRNA minicircles to prevent parkinsonian pathology.
Article Snippet: .. The total number of dopaminergic neurons within the SNc was assessed by stereology in every fourth section spanning the entire SNc using StereoInvestigator software (MBF Bioscience, Williston, VT) as previously described [15]. ..

Article Title: Acute E2/P4 loss compromises the biology and function of neurogenic niches during a vulnerable female aging period
Article Snippet: .. Stereological probes were applied using a Zeiss Imager M2 microscope (Carl Zeiss, Oberkochen Germany) equipped with StereoInvestigator software (v2019.1.3; MBF Bioscience, Williston VT), according to our published methods ( Anandhan et al ., 2021a ; Corenblum et al ., 2016 ; Madhavan et al ., 2012 ). ..

Article Title: GIT 27 modulates TLR4/Src/NOX2 signaling pathway: A potential therapeutic strategy to decrease neuroinflammation, oxidative stress and neuronal cell death in Parkinson's disease.
Article Snippet: Parkinson’s disease (PD) is a progressive neurodegenerative disorder of the central nervous system, characterized by the selective degeneration of dopaminergic neurons, particularly in the substantia nigra.. Increasing evidence points to a central role of the immune system and chronic neuroinflammation in PD pathogenesis.. Among the innate immune sensors, Toll-like receptor 4 (TLR4) has emerged as a key mediator of neuroinflammatory responses and disease progression.

Article Title: Rebamipide (Mucosta®), a clinically approved drug, alleviates neuroinflammation and dopaminergic neurodegeneration in a Parkinson's disease model.
Article Snippet: Quantitative analysis of TH-immunoreactive (IR) cells in the SNpc and optical intensity of TH-IR in the striatum (ST) was performed at × 100 and × 40 magnifications, respectively, using Stereo-investigator software (MBF Bioscience Inc., Williston, VT, USA). .. Additionally, microglial activation in the SNpc or ST was assessed at × 100 magnification using Stereoinvestigator software (MBF Bioscience Inc., Williston, VT, USA). ..

Article Title: Inhibition of PTPRS function does not affect the survival or regeneration of dopaminergic neurons but alters synaptic function in the nigrostriatal pathway.
Article Snippet: .. Stereological counts of THpositive (TH+) neurons within the SN pas compacta were conducted using stereological principles and analyzed with StereoInvestigator software (Microbrightfield, Williston, VT, USA), as previously described (Turcato et al., 2022). .. Optical fractionator sampling was performed on a Leica DM5000B microscope (Leica Microsystems, Bannockburn, IL, USA) equipped with a motorized stage. mDA groups were delineated based on TH immunolabelling, referencing a coronal atlas of the mouse brain (Franklin and Paxinos, 1997).

Microscopy:

Article Title: Targeting Neuromuscular Junction Regeneration is a Therapeutic Strategy in ALS
Article Snippet: .. The Optical Fractionator stereological technique was employed using a computer-assisted Nikon Eclipse E600 microscope equipped with the StereoInvestigator software (MicroBrightField Inc., Williston, VT, USA) ( West et al , 1991 ). .. 50 μm thick, free-floating coronal sections of each spinal cord level were cut using a cryostat (Leica), then stored in an anti-freeze solution (30% ethylene glycol, 30% glycerol, 10% PB; 189 mM NaH 2 PO 4 ; 192.5 mM NaOH; pH 7.4) at −20°C until being used.

Article Title: Acute E2/P4 loss compromises the biology and function of neurogenic niches during a vulnerable female aging period
Article Snippet: .. Stereological probes were applied using a Zeiss Imager M2 microscope (Carl Zeiss, Oberkochen Germany) equipped with StereoInvestigator software (v2019.1.3; MBF Bioscience, Williston VT), according to our published methods ( Anandhan et al ., 2021a ; Corenblum et al ., 2016 ; Madhavan et al ., 2012 ). ..

Activation Assay:

Article Title: Rebamipide (Mucosta®), a clinically approved drug, alleviates neuroinflammation and dopaminergic neurodegeneration in a Parkinson's disease model.
Article Snippet: Quantitative analysis of TH-immunoreactive (IR) cells in the SNpc and optical intensity of TH-IR in the striatum (ST) was performed at × 100 and × 40 magnifications, respectively, using Stereo-investigator software (MBF Bioscience Inc., Williston, VT, USA). .. Additionally, microglial activation in the SNpc or ST was assessed at × 100 magnification using Stereoinvestigator software (MBF Bioscience Inc., Williston, VT, USA). ..



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